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A Review of the Current Modalities for the Treatment of Papulopustular Rosacea.
Dermatol Clin. 2018 Apr; 36(2):135-150.DC

Abstract

Papulopustular rosacea is characterized by papules and pustules in the central facial region. We review the literature surrounding the treatment of papulopustular rosacea. PubMed, EMBASE, and Cochrane (Central) databases searches of articles published from 1980 to 2015 were performed using the MeSH terms or keywords "rosacea" and "clinical trial." Additional searches were performed to include rosacea and each treatment modality used. Topical metronidazole, azelaic acid, ivermectin, and oral doxycycline have the most robust data to support their use. Variation in assessment tools and a lack of clinical trial standardization makes comparison of therapeutic options difficult.

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Authors+Show Affiliations

McGregor SP
Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.
Alinia H
Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA. Electronic address: haliniamd@gmail.com.
Snyder A
Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.
Tuchayi SM
Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.
Fleischer A
Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.
Feldman SR
Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA; Department of Pathology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA; Department of Public Health Sciences, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.

MeSH

Administration, CutaneousAnti-Infective AgentsDermatologic AgentsDicarboxylic AcidsDoxycyclineHumansIvermectinMetronidazoleRosacea

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

29499797

Citation

McGregor, Sean P., et al. "A Review of the Current Modalities for the Treatment of Papulopustular Rosacea." Dermatologic Clinics, vol. 36, no. 2, 2018, pp. 135-150.
McGregor SP, Alinia H, Snyder A, et al. A Review of the Current Modalities for the Treatment of Papulopustular Rosacea. Dermatol Clin. 2018;36(2):135-150.
McGregor, S. P., Alinia, H., Snyder, A., Tuchayi, S. M., Fleischer, A., & Feldman, S. R. (2018). A Review of the Current Modalities for the Treatment of Papulopustular Rosacea. Dermatologic Clinics, 36(2), 135-150. https://doi.org/10.1016/j.det.2017.11.009
McGregor SP, et al. A Review of the Current Modalities for the Treatment of Papulopustular Rosacea. Dermatol Clin. 2018;36(2):135-150. PubMed PMID: 29499797.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A Review of the Current Modalities for the Treatment of Papulopustular Rosacea. AU - McGregor,Sean P, AU - Alinia,Hossein, AU - Snyder,Alyson, AU - Tuchayi,Sara Moradi, AU - Fleischer,Alan,Jr AU - Feldman,Steven R, Y1 - 2017/12/21/ PY - 2018/3/4/entrez PY - 2018/3/4/pubmed PY - 2018/9/13/medline KW - Azelaic acid KW - Doxycycline KW - Ivermectin KW - Management KW - Metronidazole KW - Papulopustular KW - Rosacea KW - Topical SP - 135 EP - 150 JF - Dermatologic clinics JO - Dermatol Clin VL - 36 IS - 2 N2 - Papulopustular rosacea is characterized by papules and pustules in the central facial region. We review the literature surrounding the treatment of papulopustular rosacea. PubMed, EMBASE, and Cochrane (Central) databases searches of articles published from 1980 to 2015 were performed using the MeSH terms or keywords "rosacea" and "clinical trial." Additional searches were performed to include rosacea and each treatment modality used. Topical metronidazole, azelaic acid, ivermectin, and oral doxycycline have the most robust data to support their use. Variation in assessment tools and a lack of clinical trial standardization makes comparison of therapeutic options difficult. SN - 1558-0520 UR - https://brain.unboundmedicine.com/medline/citation/29499797/A_Review_of_the_Current_Modalities_for_the_Treatment_of_Papulopustular_Rosacea_ DB - PRIME DP - Unbound Medicine ER -