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The efficacy of tea tree face wash, 1, 2-Octanediol and microblepharoexfoliation in treating Demodex folliculorum blepharitis.
Cont Lens Anterior Eye. 2018 02; 41(1):77-82.CL

Abstract

PURPOSE

To compare the efficacy of Dr Organic Tea Tree Face Wash, OcuSoft Lids Scrub Plus and the BlephEx™ device at treating of Demodex folliculorum blepharitis.

METHODS

Eighty-six subjects (33 males/36 females) were enrolled in a randomised controlled interventional treatment study. Subjects completed a dry eye symptom questionnaire and were assessed for presence of Demodex folliculorum. Subjects were divided into three groups according to treatment: Dr Organic Tea Tree Face Wash (A) (n=28), OcuSoft Lid Scrub Plus (B) (n=30), or in-house lid scrub with the BlephEx™ device before nightly lid scrubs with OcuSoft Lid Scrub Plus (C) (n=28). Subjects were advised to clean their eyelids nightly for four weeks. Each subject was re-assessed for symptoms and Demodex folliculorum blepharitis after two weeks and four weeks of treatment.

RESULTS

The quantity of Demodex folliculorum was significantly reduced after four weeks of treatment in all three groups (p<0.05). Overall, there was no difference in efficacy between the three treatments (p>0.1). Symptoms reported by subjects were significantly improved after two and four weeks of treatment (p<0.05). Overall, there was no difference in efficacy between the three treatments to reduce symptoms after two or four weeks (p= 0.813 and p=0.646 respectively).

CONCLUSION

All three methods tested have shown good ability to reduce Demodex folliculorum quantity, improve subjective symptoms and help treat Demodex folliculorum blepharitis.

Authors+Show Affiliations

Dublin Institute of Technology, Ireland. Electronic address: orla.murphy@dit.ie.Dublin Institute of Technology, Ireland.Dublin Institute of Technology, Ireland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29074306

Citation

Murphy, Orla, et al. "The Efficacy of Tea Tree Face Wash, 1, 2-Octanediol and Microblepharoexfoliation in Treating Demodex Folliculorum Blepharitis." Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association, vol. 41, no. 1, 2018, pp. 77-82.
Murphy O, O'Dwyer V, Lloyd-McKernan A. The efficacy of tea tree face wash, 1, 2-Octanediol and microblepharoexfoliation in treating Demodex folliculorum blepharitis. Cont Lens Anterior Eye. 2018;41(1):77-82.
Murphy, O., O'Dwyer, V., & Lloyd-McKernan, A. (2018). The efficacy of tea tree face wash, 1, 2-Octanediol and microblepharoexfoliation in treating Demodex folliculorum blepharitis. Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association, 41(1), 77-82. https://doi.org/10.1016/j.clae.2017.10.012
Murphy O, O'Dwyer V, Lloyd-McKernan A. The Efficacy of Tea Tree Face Wash, 1, 2-Octanediol and Microblepharoexfoliation in Treating Demodex Folliculorum Blepharitis. Cont Lens Anterior Eye. 2018;41(1):77-82. PubMed PMID: 29074306.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The efficacy of tea tree face wash, 1, 2-Octanediol and microblepharoexfoliation in treating Demodex folliculorum blepharitis. AU - Murphy,Orla, AU - O'Dwyer,Veronica, AU - Lloyd-McKernan,Aoife, Y1 - 2017/10/23/ PY - 2017/06/19/received PY - 2017/10/12/revised PY - 2017/10/13/accepted PY - 2017/10/28/pubmed PY - 2019/1/12/medline PY - 2017/10/28/entrez KW - BlephEx(TM) KW - Blepharitis KW - Demodex folliculorum KW - OcuSoft plus KW - Tea tree face wash KW - Treatment SP - 77 EP - 82 JF - Contact lens & anterior eye : the journal of the British Contact Lens Association JO - Cont Lens Anterior Eye VL - 41 IS - 1 N2 - PURPOSE: To compare the efficacy of Dr Organic Tea Tree Face Wash, OcuSoft Lids Scrub Plus and the BlephEx™ device at treating of Demodex folliculorum blepharitis. METHODS: Eighty-six subjects (33 males/36 females) were enrolled in a randomised controlled interventional treatment study. Subjects completed a dry eye symptom questionnaire and were assessed for presence of Demodex folliculorum. Subjects were divided into three groups according to treatment: Dr Organic Tea Tree Face Wash (A) (n=28), OcuSoft Lid Scrub Plus (B) (n=30), or in-house lid scrub with the BlephEx™ device before nightly lid scrubs with OcuSoft Lid Scrub Plus (C) (n=28). Subjects were advised to clean their eyelids nightly for four weeks. Each subject was re-assessed for symptoms and Demodex folliculorum blepharitis after two weeks and four weeks of treatment. RESULTS: The quantity of Demodex folliculorum was significantly reduced after four weeks of treatment in all three groups (p<0.05). Overall, there was no difference in efficacy between the three treatments (p>0.1). Symptoms reported by subjects were significantly improved after two and four weeks of treatment (p<0.05). Overall, there was no difference in efficacy between the three treatments to reduce symptoms after two or four weeks (p= 0.813 and p=0.646 respectively). CONCLUSION: All three methods tested have shown good ability to reduce Demodex folliculorum quantity, improve subjective symptoms and help treat Demodex folliculorum blepharitis. SN - 1476-5411 UR - https://brain.unboundmedicine.com/medline/citation/29074306/The_efficacy_of_tea_tree_face_wash_1_2_Octanediol_and_microblepharoexfoliation_in_treating_Demodex_folliculorum_blepharitis_ DB - PRIME DP - Unbound Medicine ER -