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Ivermectin 1% cream for rosacea.
Skin Therapy Lett. 2015 Jul-Aug; 20(4):9-11.ST

Abstract

The etiology of papulopustular rosacea (PPR) is not well understood yet appears to involve both the innate and adaptive immune response in addition to possible infestation with Demodex mites. Current treatments for PPR consist mainly of antibiotics. Ivermectin cream 1%, a new topical treatment for PPR, possesses both anti-inflammatory and anti-parasitic properties. After 12 weeks of treatment, subjects treated with ivermectin cream 1% had significantly greater reductions in PPR symptoms and enhanced diseaserelated quality of life improvements compared to subjects who received vehicle. Furthermore, PPR symptoms continued to improve with prolonged treatment (40 weeks). Ivermectin cream 1% offers a multi-pronged approach to combat the complex pathophysiology of rosacea.

Authors+Show Affiliations

Wayne State University, Detroit, MI, USA; Mediprobe Research Inc., London, ON, Canada.Mediprobe Research Inc., London, ON, Canada.Mediprobe Research Inc., London, ON, Canada; Department of Medicine, University of Toronto School of Medicine, Toronto, ON, Canada.Henry Ford Medical Center, Department of Dermatology, Detroit, MI, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26382711

Citation

Gupta, G, et al. "Ivermectin 1% Cream for Rosacea." Skin Therapy Letter, vol. 20, no. 4, 2015, pp. 9-11.
Gupta G, Daigle D, Gupta AK, et al. Ivermectin 1% cream for rosacea. Skin Therapy Lett. 2015;20(4):9-11.
Gupta, G., Daigle, D., Gupta, A. K., & Gold, L. S. (2015). Ivermectin 1% cream for rosacea. Skin Therapy Letter, 20(4), 9-11.
Gupta G, et al. Ivermectin 1% Cream for Rosacea. Skin Therapy Lett. 2015 Jul-Aug;20(4):9-11. PubMed PMID: 26382711.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ivermectin 1% cream for rosacea. AU - Gupta,G, AU - Daigle,D, AU - Gupta,A K, AU - Gold,L S, PY - 2015/9/19/entrez PY - 2015/9/19/pubmed PY - 2016/4/15/medline SP - 9 EP - 11 JF - Skin therapy letter JO - Skin Therapy Lett VL - 20 IS - 4 N2 - The etiology of papulopustular rosacea (PPR) is not well understood yet appears to involve both the innate and adaptive immune response in addition to possible infestation with Demodex mites. Current treatments for PPR consist mainly of antibiotics. Ivermectin cream 1%, a new topical treatment for PPR, possesses both anti-inflammatory and anti-parasitic properties. After 12 weeks of treatment, subjects treated with ivermectin cream 1% had significantly greater reductions in PPR symptoms and enhanced diseaserelated quality of life improvements compared to subjects who received vehicle. Furthermore, PPR symptoms continued to improve with prolonged treatment (40 weeks). Ivermectin cream 1% offers a multi-pronged approach to combat the complex pathophysiology of rosacea. SN - 1201-5989 UR - https://brain.unboundmedicine.com/medline/citation/26382711/Ivermectin_1_cream_for_rosacea_ DB - PRIME DP - Unbound Medicine ER -