Tags

Type your tag names separated by a space and hit enter

The treatment of rosacea with topical ivermectin.
Drugs Today (Barc). 2015 Apr; 51(4):243-50.DT

Abstract

The treatment of rosacea is challenging because several pathophysiologic processes may be involved, including neurovascular dysregulation and alterations in innate immune status. Demodex mites may play a role in the latter mechanism. Topical ivermectin is a new therapeutic modality which demonstrates antiparasitic and anti-inflammatory properties. This article reviews published evidence related to the efficacy and safety of topical ivermectin. PubMed was utilized to search for key words "topical ivermectin", "ivermectin cream" and "rosacea". Three clinical trials were found that studied topical ivermectin as a treatment option for rosacea. Ivermectin was effective, safe and well tolerated.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Ali ST
Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Alinia H
Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. haliniamd@gmail.com.
Feldman SR
Center for Dermatology Research, Department of Dermatology; Department of Pathology; Departments of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

MeSH

AcaricidesAdministration, TopicalAnimalsClinical Trials as TopicHumansIvermectinMitesRosaceaTreatment Outcome

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

26020066

Citation

Ali, S T., et al. "The Treatment of Rosacea With Topical Ivermectin." Drugs of Today (Barcelona, Spain : 1998), vol. 51, no. 4, 2015, pp. 243-50.
Ali ST, Alinia H, Feldman SR. The treatment of rosacea with topical ivermectin. Drugs Today (Barc). 2015;51(4):243-50.
Ali, S. T., Alinia, H., & Feldman, S. R. (2015). The treatment of rosacea with topical ivermectin. Drugs of Today (Barcelona, Spain : 1998), 51(4), 243-50. https://doi.org/10.1358/dot.2015.51.4.2318439
Ali ST, Alinia H, Feldman SR. The Treatment of Rosacea With Topical Ivermectin. Drugs Today (Barc). 2015;51(4):243-50. PubMed PMID: 26020066.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The treatment of rosacea with topical ivermectin. AU - Ali,S T, AU - Alinia,H, AU - Feldman,S R, PY - 2015/5/29/entrez PY - 2015/5/29/pubmed PY - 2015/10/17/medline KW - Clinical trials KW - Demodex KW - Ivermectin cream KW - Papulopustular rosacea KW - Rosacea KW - Topical ivermectin SP - 243 EP - 50 JF - Drugs of today (Barcelona, Spain : 1998) JO - Drugs Today (Barc) VL - 51 IS - 4 N2 - The treatment of rosacea is challenging because several pathophysiologic processes may be involved, including neurovascular dysregulation and alterations in innate immune status. Demodex mites may play a role in the latter mechanism. Topical ivermectin is a new therapeutic modality which demonstrates antiparasitic and anti-inflammatory properties. This article reviews published evidence related to the efficacy and safety of topical ivermectin. PubMed was utilized to search for key words "topical ivermectin", "ivermectin cream" and "rosacea". Three clinical trials were found that studied topical ivermectin as a treatment option for rosacea. Ivermectin was effective, safe and well tolerated. SN - 1699-3993 UR - https://brain.unboundmedicine.com/medline/citation/26020066/The_treatment_of_rosacea_with_topical_ivermectin_ DB - PRIME DP - Unbound Medicine ER -