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Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin.
JAMA Dermatol. 2014 Jan; 150(1):61-3.JD

Abstract

IMPORTANCE

There is a limited therapeutic armamentarium for recalcitrant cases of childhood rosacea.

OBSERVATIONS

We report the case of a 12-year-old girl who presented with severe ocular and cutaneous rosacea unresponsive to oral doxycycline, oral isotretinoin, and topical tacrolimus. A biopsy specimen showed numerous mites within the folliculosebaceous unit. Treatment with a single dose of oral ivermectin achieved resolution of her symptoms.

CONCLUSIONS AND RELEVANCE

The causative role of Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like refractory eruptions. In such cases, treatment with ivermectin can be beneficial.

Authors+Show Affiliations

Department of Dermatology, School of Medicine, University of New Mexico, Albuquerque.Department of Dermatology, Hospital Infantil del Niño Jesús, Madrid, Spain.Department of Ophthalmology, Hospital Infantil del Niño Jesús, Madrid, Spain.Department of Pathology, Hospital Infantil del Niño Jesús, Madrid, Spain.Department of Dermatology, Hospital Infantil del Niño Jesús, Madrid, Spain.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24284904

Citation

Brown, Megan, et al. "Severe Demodexfolliculorum-associated Oculocutaneous Rosacea in a Girl Successfully Treated With Ivermectin." JAMA Dermatology, vol. 150, no. 1, 2014, pp. 61-3.
Brown M, Hernández-Martín A, Clement A, et al. Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin. JAMA Dermatol. 2014;150(1):61-3.
Brown, M., Hernández-Martín, A., Clement, A., Colmenero, I., & Torrelo, A. (2014). Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin. JAMA Dermatology, 150(1), 61-3. https://doi.org/10.1001/jamadermatol.2013.7688
Brown M, et al. Severe Demodexfolliculorum-associated Oculocutaneous Rosacea in a Girl Successfully Treated With Ivermectin. JAMA Dermatol. 2014;150(1):61-3. PubMed PMID: 24284904.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin. AU - Brown,Megan, AU - Hernández-Martín,Angela, AU - Clement,Ana, AU - Colmenero,Isabel, AU - Torrelo,Antonio, PY - 2013/11/29/entrez PY - 2013/11/29/pubmed PY - 2014/3/14/medline SP - 61 EP - 3 JF - JAMA dermatology JO - JAMA Dermatol VL - 150 IS - 1 N2 - IMPORTANCE: There is a limited therapeutic armamentarium for recalcitrant cases of childhood rosacea. OBSERVATIONS: We report the case of a 12-year-old girl who presented with severe ocular and cutaneous rosacea unresponsive to oral doxycycline, oral isotretinoin, and topical tacrolimus. A biopsy specimen showed numerous mites within the folliculosebaceous unit. Treatment with a single dose of oral ivermectin achieved resolution of her symptoms. CONCLUSIONS AND RELEVANCE: The causative role of Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like refractory eruptions. In such cases, treatment with ivermectin can be beneficial. SN - 2168-6084 UR - https://brain.unboundmedicine.com/medline/citation/24284904/Severe_demodexfolliculorum_associated_oculocutaneous_rosacea_in_a_girl_successfully_treated_with_ivermectin_ L2 - https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2013.7688 DB - PRIME DP - Unbound Medicine ER -